Transmembrane activator and CAML interactor

TNFRSF13B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XU1, 1XUT
Identifiers
Aliases	TNFRSF13B, CD267, CVID, CVID2, RYZN, TACI, TNFRSF14B, IGAD2, tumor necrosis factor receptor superfamily member 13B, TNF receptor superfamily member 13B
External IDs	OMIM: 604907 MGI: 1889411 HomoloGene: 49320 GeneCards: TNFRSF13B
Gene location (Human)
Chr.	Chromosome 17 (human)
End	16,972,118 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	61,040,198 bp
RNA expression pattern
	Top expressed in
	spleen; ; lymph node; ; bone marrow cells; ; gastrocnemius muscle; ; cecum; ; appendix; ; parotid gland; ; pylorus; ; left ventricle; ; superior surface of tongue;
	Top expressed in
	spleen; ; bone marrow; ; blood; ; thymus; ; subcutaneous adipose tissue; ; yolk sac; ; white adipose tissue; ; submandibular gland; ; duodenum; ; left lung;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; signaling receptor activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; plasma membrane;
Biological process	cell surface receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; adaptive immune response; immune system process; B cell homeostasis; hematopoietic progenitor cell differentiation; negative regulation of B cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	23495
	57916
	ENSG00000240505
	ENSMUSG00000010142
	O14836
	Q9ET35
	NM_012452
	NM_021349
	NP_036584
	NP_067324
	Wikidata
View/Edit Human	View/Edit Mouse

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) is a protein that in humans is encoded by the TNFRSF13B gene.

TNFRSF13B is a transmembrane protein of the TNF receptor superfamily found predominantly on the surface of B cells, which are an important part of the immune system. TACI recognizes three ligands: APRIL, BAFF and CAML.

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