Wee1

Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). Wee1 has a molecular mass of 96 kDa and is a key regulator of cell cycle progression. It influences cell size by inhibiting the entry into mitosis, through inhibiting Cdk1. Wee1 has homologues in many other organisms, including mammals.

Wee1
Crystal structure of human Wee1
Identifiers
SymbolMitosis inhibitor protein kinase Wee1
Alt. symbolswee1 dual specificity protein kinase Wee1
NCBI gene2539123
UniProtP07527
Other data
EC number2.7.11.1
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StructuresSwiss-model
DomainsInterPro
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