Schotten–Baumann reaction
The Schotten–Baumann reaction is a method to synthesize amides from amines and acid chlorides:
| Schotten-Baumann reaction | |
|---|---|
| Named after | Carl Schotten Eugen Baumann |
| Reaction type | Condensation reaction |
| Identifiers | |
| Organic Chemistry Portal | schotten-baumann-reaction |
| RSC ontology ID | RXNO:0000165 |
Schotten–Baumann reaction also refers to the conversion of acid chloride to esters. The reaction was first described in 1883 by German chemists Carl Schotten and Eugen Baumann.
The name "Schotten–Baumann reaction conditions" often indicate the use of a two-phase solvent system, consisting of water and an organic solvent. The base within the water phase neutralizes the acid, generated in the reaction, while the starting materials and product remain in the organic phase, often dichloromethane or diethyl ether.
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