Pyrazine

Pyrazine is a heterocyclic aromatic organic compound with the chemical formula C4H4N2. It is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. It is a "deliquescent crystal or wax-like solid with a pungent, sweet, corn-like, nutty odour".

Pyrazine
Names
Preferred IUPAC name
Pyrazine
Other names
1,4-Diazabenzene, p-Diazine, 1,4-Diazine, Paradiazine, Piazine, UN 1325
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.005.480
EC Number
  • 206-027-6
UNII
  • InChI=1S/C4H4N2/c1-2-6-4-3-5-1/h1-4H Y
    Key: KYQCOXFCLRTKLS-UHFFFAOYSA-N Y
  • InChI=1/C4H4N2/c1-2-6-4-3-5-1/h1-4H
  • c1cnccn1
Properties
C4H4N2
Molar mass 80.09 g/mol
Appearance White crystals
Density 1.031 g/cm3
Melting point 52 °C (126 °F; 325 K)
Boiling point 115 °C (239 °F; 388 K)
Soluble
Acidity (pKa) 0.37 (protonated pyrazine)
-37.6·10−6 cm3/mol
Hazards
GHS labelling:
Danger
H228, H315, H319, H335
P210, P261, P305+P351+P338
NFPA 704 (fire diamond)
2
2
0
Flash point 55 °C (131 °F; 328 K) c.c.
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Pyrazine and a variety of alkylpyrazines are flavor and aroma compounds found in baked and roasted goods. Tetramethylpyrazine (also known as ligustrazine) is reported to scavenge superoxide anion and decrease nitric oxide production in human Granulocytes.

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