Oxamic acid

Oxamic acid is an organic compound with the formula NH2C(O)COOH. It is a white, water-soluble solid. It is the monoamide of oxalic acid. Oxamic acid inhibits lactate dehydrogenase A. The active site of lactate dehydrogenase (LDH) is closed off once oxamic acid attaches to the LDH-NADH complex, effectively inhibiting it.

Oxamic acid

Ball and stick model of oxamic acid
Names
Preferred IUPAC name
Oxamic acid
Other names
Amino(oxo)acetic acid
2-Amino-2-oxoacetic acid
2-oxoglycine
Aminooxoacetic acid
Oxalamic acid
Oxamidic acid
2-Amino-2-oxoethanoic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.768
UNII
  • C(=O)(C(=O)O)N
Properties
NH2C(O)COOH
Molar mass 89.050 g·mol−1
Appearance White solid
Melting point 209 °C
Soluble
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Oxamic acid also has applications in polymer chemistry. It increases the water solubility of certain polymers, including polyester, epoxide, and acrylic upon binding with them.

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