Lactate dehydrogenase A

LDHA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1I10, 4AJP, 4JNK, 4L4R, 4L4S, 4M49, 4OJN, 4OKN, 4QO7, 4QO8, 4QSM, 4QT0, 4R68, 4R69, 4RLS, 4ZVV
Identifiers
Aliases	LDHA, GSD11, HEL-S-133P, LDH1, LDHM, PIG19, lactate dehydrogenase A
External IDs	OMIM: 150000 MGI: 96759 HomoloGene: 56495 GeneCards: LDHA
Gene location (Human)
Chr.	Chromosome 11 (human)
End	18,408,425 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	46,505,051 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; muscle of leg; ; Achilles tendon; ; ascending aorta; ; right adrenal gland; ; gastrocnemius muscle; ; appendix; ; left adrenal gland; ; subcutaneous adipose tissue; ; duodenum;
	Top expressed in
	otic placode; ; somite; ; primitive streak; ; triceps brachii muscle; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; saccule; ; tibialis anterior muscle; ; temporal muscle; ; skeletal muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; NAD binding; lactate dehydrogenase activity; kinase binding; protein binding; catalytic activity; identical protein binding; oxidoreductase activity; L-lactate dehydrogenase activity; cadherin binding;
Cellular component	cytoplasm; membrane; extracellular exosome; nucleus; cytosol;
Biological process	post-embryonic animal organ development; lactate metabolic process; response to hypoxia; glycolytic process; response to organic cyclic compound; substantia nigra development; response to nutrient; carboxylic acid metabolic process; response to glucose; NAD metabolic process; response to estrogen; pyruvate metabolic process; positive regulation of apoptotic process; response to cAMP; response to hydrogen peroxide; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	3939
	16828
	ENSG00000134333; ENSG00000288299
	ENSMUSG00000063229
	P00338
	P06151
	NM_001135239; NM_001165414; NM_001165415; NM_001165416; NM_005566
	NM_001136069; NM_010699
	NP_001128711; NP_001158886; NP_001158887; NP_001158888; NP_005557
	NP_001129541; NP_034829
	Wikidata
View/Edit Human	View/Edit Mouse

Lactate dehydrogenase A (LDHA) is an enzyme which in humans is encoded by the LDHA gene. It is a monomer of Lactate dehydrogenase, which exists as a tetramer. The other main subunit is lactate dehydrogenase B (LDHB).

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