ORC1

ORC1
Identifiers
Aliases	ORC1, HSORC1L, PARC1, origin recognition complex subunit 1
External IDs	OMIM: 601902 MGI: 1328337 HomoloGene: 31221 GeneCards: ORC1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	52,404,423 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	108,472,030 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow; ; secondary oocyte; ; rectum; ; stromal cell of endometrium; ; bone marrow cells; ; lymph node; ; appendix; ; spongy bone; ; islet of Langerhans;
	Top expressed in
	secondary oocyte; ; primitive streak; ; morula; ; abdominal wall; ; otic placode; ; yolk sac; ; blood; ; autopod region; ; foot; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; chromatin binding; protein binding; ATP binding; DNA replication origin binding; metal ion binding;
Cellular component	nuclear origin of replication recognition complex; plasma membrane; nucleolus; origin recognition complex; nucleus; nucleoplasm; cytosol;
Biological process	G1 phase; DNA replication; regulation of transcription involved in G1/S transition of mitotic cell cycle; DNA replication initiation; G1/S transition of mitotic cell cycle; mitotic cell cycle; mitotic DNA replication checkpoint signaling;
	Sources:Amigo / QuickGO
Orthologs
	4998
	18392
	ENSG00000085840
	ENSMUSG00000028587
	Q13415
	Q9Z1N2
	NM_001190818; NM_001190819; NM_004153
	NM_001014425; NM_011015
	NP_001177747; NP_001177748; NP_004144
	NP_035145
	Wikidata
View/Edit Human	View/Edit Mouse

Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene. It is closely related to CDC6, and both are the same protein in archaea.

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