Miraculin

Miraculin is a taste modifier, a glycoprotein extracted from the fruit of Synsepalum dulcificum. The berry, also known as the miracle fruit, was documented by explorer Chevalier des Marchais, who searched for many different fruits during a 1725 excursion to its native West Africa.

Miraculin glycoprotein
Crystallographic structure of a dimeric miraculin-like protein from seeds of Murraya koenigii.
Identifiers
OrganismSynsepalum dulcificu
SymbolMIRA_RICDU
PDB3IIR
UniProtP13087
Search for
StructuresSwiss-model
DomainsInterPro

Miraculin itself does not taste sweet. When taste buds are exposed to miraculin, the protein binds to the sweetness receptors. This causes normally sour-tasting acidic foods, such as citrus, to be perceived as sweet. The effect can last for one or two hours.

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