Mecasermin rinfabate
Mecasermin rinfabate (INN, USAN) (brand name Iplex), also known as rhIGF-1/rhIGFBP-3, is a drug consisting of recombinant human insulin-like growth factor 1 (IGF-1) and recombinant human insulin-like growth factor binding protein-3 (IGFBP-3) which is used for the treatment of amyotrophic lateral sclerosis (Lou Gehrig's disease).
| Combination of | |
|---|---|
| IGF-1 | Growth factor |
| IGFBP-3 | Binding protein |
| Clinical data | |
| Trade names | Iplex |
| AHFS/Drugs.com | Monograph |
| Routes of administration | Injection |
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It is similar in action to mecasermin, but with fewer side effects (such as hypoglycemia).
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