Mapatumumab
Mapatumumab (HGS-ETR1) is an experimental human monoclonal antibody undergoing clinical trials for the treatment of cancer. It targets TRAIL-R1, also known as DR4, which is expressed on the surface of many tumor cell types.
Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | TRAIL-receptor (death receptor 4) |
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Chemical and physical data | |
Formula | C6748H10408N1800O2092S52 |
Molar mass | 151891.12 g·mol−1 |
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