Macrophage inflammatory protein

chemokine (C-C motif) ligand 4
chemokine (C-C motif) ligand 4
	Human Mip-1β dimer. PDB 1hum. Disulfide bonds highlighted.
Identifiers
Symbol	CCL4
Alt. symbols	SCYA4, MIP-1β, LAG1
NCBI gene	6351
HGNC	10630
OMIM	182284
PDB	1HUM More structures
RefSeq	NM_002984
UniProt	P13236
Other data
Locus	Chr. 17 q21-q23
Structures
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Structures	Swiss-model
Domains	InterPro

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Structures	Swiss-model
Domains	InterPro

chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3
	Human Mip-1α dimer D26A mutant. PDB 1b53. Disulfide bonds highlighted.
Identifiers
Symbol	CCL3
Alt. symbols	SCYA3, MIP-1α
NCBI gene	6348
HGNC	10627
OMIM	182283
PDB	1B50 More structures
RefSeq	NM_002983
UniProt	P10147
Other data
Locus	Chr. 17 q12
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β, renamed CCL3 and CCL4 respectively, since 2000. However, other names are sometimes encountered in older literature, such as LD78α, AT 464.1 and GOS19-1 for human CCL3 and AT 744, Act-2, LAG-1, HC21 and G-26 for human CCL4. Other macrophage inflammatory proteins include MIP-2, MIP-3 and MIP-5.

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