Link domain
A Link domain or Link module, also known as Xlink domain (X for extracellular), is a protein domain that binds to hyaluronic acid. It is important in blood cell migration and apoptosis. The link domain is found in some extracellular proteins in vertebrates such as the hyalectans. It appears to be involved in extracellular matrix assembly and stability, cell adhesion, and migration.
| Link domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of the hyaluronan-binding domain of human CD44 | |||||||||
| Identifiers | |||||||||
| Symbol | LINK | ||||||||
| Pfam | PF00193 | ||||||||
| Pfam clan | CL0056 | ||||||||
| InterPro | IPR000538 | ||||||||
| SMART | SM00445 | ||||||||
| PROSITE | PDOC00955 | ||||||||
| SCOP2 | 1o7b / SCOPe / SUPFAM | ||||||||
| CDD | cd01102 | ||||||||
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