IFITM1

IFITM1
Identifiers
Aliases	IFITM1, 9-27, CD225, DSPA2a, IFI17, LEU13, interferon induced transmembrane protein 1
External IDs	OMIM: 604456 HomoloGene: 74501 GeneCards: IFITM1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	315,272 bp
RNA expression pattern
	Top expressed in
	canal of the cervix; ; left uterine tube; ; right uterine tube; ; corpus epididymis; ; spleen; ; blood; ; right lobe of thyroid gland; ; pericardium; ; subcutaneous adipose tissue; ; left lobe of thyroid gland;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; membrane; plasma membrane; protein-containing complex;
Biological process	negative regulation of viral entry into host cell; response to interferon-gamma; ossification; immune system process; response to virus; response to interferon-beta; response to biotic stimulus; cell surface receptor signaling pathway; negative regulation of viral genome replication; negative regulation of cell migration; positive regulation of osteoblast differentiation; defense response to virus; type I interferon signaling pathway; response to interferon-alpha; regulation of immune response; innate immune response; negative regulation of cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	8519
	n/a
	ENSG00000185885
	n/a
	P13164
	n/a
	NM_003641
	n/a
	NP_003632
	n/a
	Wikidata
View/Edit Human

Interferon-induced transmembrane protein 1 is a protein that in humans is encoded by the IFITM1 gene. IFITM1 has also recently been designated CD225 (cluster of differentiation 225). This protein has several additional names: fragilis (human homolog of the mouse protein), IFI17 [interferon-induced protein 17], 9-27 [Interferon-inducible protein 9-27] and Leu13.

IFITM1 is a member of the IFITM family (Interferon-induced transmembrane protein) which is encoded by IFITM genes. The human IFITM genes locate on chromosome 11 and have four members: IFITM1, IFITM2, IFITM3 and IFITM5. While the mouse Ifitm genes locate on chromosome 7 and 16 and have six members: Ifitm1, Ifitm2, Ifitm3, Ifitm5, Ifitm6 and Ifitm7.

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