Ethanolamine

Ethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is a naturally occurring organic chemical compound with the formula HOCH
2CH
2NH
2 or C
2H
7NO. The molecule is bifunctional, containing both a primary amine and a primary alcohol. Ethanolamine is a colorless, viscous liquid with an odor reminiscent of ammonia.

Ethanolamine
Names
Preferred IUPAC name
2-Aminoethan-1-ol
Other names
  • 2-Aminoethanol
  • 2-Amino-1-ethanol
  • Ethanolamine (not recommended)
  • Monoethanolamine
  • β-Aminoethanol
  • β-hydroxyethylamine
  • β-Aminoethyl alcohol
  • Glycinol
  • Olamine
  • MEA
  • Ethylolamine
  • 2-Hydroxyethylamine
  • Colamine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.004.986
EC Number
  • 205-483-3
KEGG
RTECS number
  • KJ5775000
UNII
  • InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2 Y
    Key: HZAXFHJVJLSVMW-UHFFFAOYSA-N Y
  • InChI=1/C2H7NO/c3-1-2-4/h4H,1-3H2
    Key: HZAXFHJVJLSVMW-UHFFFAOYAD
  • NCCO
Properties
C2H7NO
Molar mass 61.084 g·mol−1
Appearance Viscous colourless liquid
Odor Unpleasant ammonia-like odour
Density 1.0117 g/cm3
Melting point 10.3 °C (50.5 °F; 283.4 K)
Boiling point 170 °C (338 °F; 443 K)
Miscible
Vapor pressure 64 Pa (20 °C)
Acidity (pKa) 9.50
1.4539 (20 °C)
Hazards
GHS labelling:
Danger
H302, H312, H314, H332, H335, H412
P261, P273, P303+P361+P353, P305+P351+P338
NFPA 704 (fire diamond)
3
2
0
Flash point 85 °C (185 °F; 358 K) (closed cup)
410 °C (770 °F; 683 K)
Explosive limits 5.5–17%
Lethal dose or concentration (LD, LC):
  • 3320 mg/kg (rat, oral)
  • 620 mg/kg (guinea pig, oral)
  • 2050 mg/kg (rat, oral)
  • 1475 mg/kg (mouse, oral)
  • 1000 mg/kg (rabbit, oral)
  • 700 mg/kg (mouse, oral)
  • 1720–1970 mg/kg (rat, oral)
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA: 3 ppm (6 mg/m3)
REL (Recommended)
  • TWA: 3 ppm (8 mg/m3)
  • ST: 6 ppm (15 mg/m3)
IDLH (Immediate danger)
 30 ppm
Safety data sheet (SDS) Sigma
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Ethanolamine is commonly called monoethanolamine or MEA in order to be distinguished from diethanolamine (DEA) and triethanolamine (TEA). The ethanolamines comprise a group of amino alcohols. A class of antihistamines is identified as ethanolamines, which includes carbinoxamine, clemastine, dimenhydrinate, chlorphenoxamine, diphenhydramine and doxylamine.

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