DMPU

N,N′-Dimethylpropyleneurea (DMPU) is a cyclic urea sometimes used as a polar, aprotic organic solvent. In 1985, Dieter Seebach showed that it is possible to replace the suspected carcinogen hexamethylphosphoramide (HMPA) with DMPU.

DMPU
Names
Preferred IUPAC name
1,3-Dimethyl-1,3-diazinan-2-one
Other names
N,N′-Dimethyl-N,N′-trimethyleneurea
N,N′-Dimethylpropyleneurea
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
Identifiers
3D model (JSmol)
Abbreviations DMPU
ChEMBL
ChemSpider
ECHA InfoCard 100.027.841
EC Number
  • 230-625-6
  • InChI=1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3 Y
    Key: GUVUOGQBMYCBQP-UHFFFAOYSA-N Y
  • InChI=1/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3
    Key: GUVUOGQBMYCBQP-UHFFFAOYAB
  • O=C1N(C)CCCN1C
Properties
C6H12N2O
Molar mass 128.175 g·mol−1
Density 1.064 g/cm3
Melting point −20 °C; −4 °F; 253 K
Boiling point 246.5 °C (475.7 °F; 519.6 K) (Source)
miscible
1.4875-1.4895
Hazards
GHS labelling:
Danger
H302, H318, H361f
P201, P202, P264, P270, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P405, P501
Flash point 121 °C (250 °F; 394 K)
Safety data sheet (SDS) External MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references
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