Alanine aminopeptidase

ANPEP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4FYQ, 4FYR, 4FYS, 4FYT
Identifiers
Aliases	ANPEP, APN, CD13, GP150, LAP1, P150, PEPN, alanyl aminopeptidase, membrane, AP-M, hAPN, AP-N
External IDs	OMIM: 151530 MGI: 5000466 HomoloGene: 68163 GeneCards: ANPEP
Gene location (Human)
Chr.	Chromosome 15 (human)
End	89,815,401 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	79,510,807 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; body of pancreas; ; right lobe of liver; ; stromal cell of endometrium; ; gallbladder; ; kidney; ; blood; ; monocyte; ; minor salivary gland;
	Top expressed in
	jejunum; ; duodenum; ; ileum; ; crypt of lieberkuhn of small intestine; ; lip; ; right lobe of liver; ; epithelium of stomach; ; lacrimal gland; ; aortic valve; ; intestinal villus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	virus receptor activity; zinc ion binding; metalloaminopeptidase activity; hydrolase activity; metal ion binding; peptidase activity; aminopeptidase activity; metallopeptidase activity; peptide binding; signaling receptor activity;
Cellular component	lysosomal membrane; integral component of membrane; membrane; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; extracellular exosome; extracellular space; nucleus; plasma membrane; secretory granule membrane; cytoplasm;
Biological process	viral process; peptide catabolic process; proteolysis; viral entry into host cell; multicellular organism development; cell differentiation; angiogenesis; neutrophil degranulation; signal transduction; cell-cell signaling; regulation of blood pressure;
	Sources:Amigo / QuickGO
Orthologs
	290
	16790
	ENSG00000166825
	ENSMUSG00000039062
	P15144
	P97449
	NM_001150; NM_001381923; NM_001381924
	NM_008486
	NP_001141; NP_001368852; NP_001368853
	NP_032512
	Wikidata
View/Edit Human	View/Edit Mouse

Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.

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