Interleukin-3 receptor
The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system.
| interleukin 3 receptor, alpha | |
|---|---|
| Identifiers | |
| Symbol | IL3RA |
| Alt. symbols | CD123 |
| HGNC | 6012 |
| OMIM | 308385 |
| Other data | |
| Locus | Chr. X p22.3 |
| interleukin 3 receptor, Y-Chromosomal | |
|---|---|
| Identifiers | |
| Symbol | IL3RA |
| Alt. symbols | IL3RY, IL3RAY |
| NCBI gene | 3563 |
| HGNC | 6012 |
| OMIM | 430000 |
| Other data | |
| Locus | Chr. Y p11.3 |
The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes.
The receptor belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CD131) subunit.
The gene for the alpha subunit is 40 kilobases long and has 12 exons.
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