Brunner's glands

Brunner's glands (or duodenal glands) are compound tubuloalveolar submucosal glands found in that portion of the duodenum proximal to the hepatopancreatic sphincter (i.e sphincter of Oddi).

Brunner's glands
Section of duodenum. (Duodenal glands in submucosa are labeled at right, fourth from the top.)
Details
SystemDigestive system
LocationDuodenum
Identifiers
Latinglandulae duodenales
MeSHD002011
TA98A05.6.02.017
TA22957
FMA71622
Anatomical terms of microanatomy

Their main function is to secrete alkaline (bicarbonate-containing) mucous in order to:

  • protect the duodenum from the acidic content of chyme (which enters the duodenum from the stomach),
  • provide an alkaline environment which promotes the acitity of intestinal enzymes,
  • lubricate the intestinal walls.

They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them, Johann Conrad Brunner.

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