α-Amylase
α-Amylase is an enzyme (EC 3.2.1.1; systematic name 4-α-D-glucan glucanohydrolase) that hydrolyses α bonds of large, α-linked polysaccharides, such as starch and glycogen, yielding shorter chains thereof, dextrins, and maltose, through the following biochemical process:
- Endohydrolysis of (1→4)-α-D-glucosidic linkages in polysaccharides containing three or more (1→4)-α-linked D-glucose units
| α-Amylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.1 | ||||||||
| CAS no. | 9000-90-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| GH13 catalytic domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Cyclodextrin glucanotransferase (e.c.2.4.1.19) (cgtase) | |||||||||
| Identifiers | |||||||||
| Symbol | Alpha-amylase | ||||||||
| Pfam | PF00128 | ||||||||
| Pfam clan | CL0058 | ||||||||
| InterPro | IPR006047 | ||||||||
| SCOP2 | 1ppi / SCOPe / SUPFAM | ||||||||
| OPM superfamily | 117 | ||||||||
| OPM protein | 1wza | ||||||||
| CAZy | GH13 | ||||||||
| CDD | cd11338 | ||||||||
| |||||||||
| Alpha-amylase C-terminal beta-sheet domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Crystal structure of barley alpha-amylase isozyme 1 (amy1) inactive mutant d180a in complex with maltoheptaose | |||||||||
| Identifiers | |||||||||
| Symbol | Alpha-amyl_C2 | ||||||||
| Pfam | PF07821 | ||||||||
| InterPro | IPR012850 | ||||||||
| |||||||||
| Alpha amylase, C-terminal all-beta domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
maltotriose complex of preconditioned cyclodextrin glycosyltransferase mutant | |||||||||
| Identifiers | |||||||||
| Symbol | Alpha-amylase_C | ||||||||
| Pfam | PF02806 | ||||||||
| Pfam clan | CL0369 | ||||||||
| InterPro | IPR006048 | ||||||||
| SCOP2 | 1ppi / SCOPe / SUPFAM | ||||||||
| |||||||||
It is the major form of amylase found in humans and other mammals. It is also present in seeds containing starch as a food reserve, and is secreted by many fungi. It is a member of glycoside hydrolase family 13.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.