2C (psychedelics)

2C (2C-x) is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of a benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolically stable and longer acting compounds. Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970s and 1980s and published in his book PiHKAL (Phenethylamines i Have Known And Loved). Shulgin also coined the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group.

Nomenclature R3 R4 2D Structure CAS number
2C-B H Br 66142-81-2
2C-Bn H CH2C6H5
2C-Bu H CH2CH2CH2CH3
2C-C H Cl 88441-14-9
2C-C-3 Cl Cl
2C-CN H C≡N 88441-07-0
2C-CP H C3H5
2C-D H CH3 24333-19-5
2C-E H CH2CH3 71539-34-9
2C-EF H CH2CH2F 1222814-77-8
2C-F H F 207740-15-6
2C-G CH3 CH3 207740-18-9
2C-G-1 CH2
2C-G-2 (CH2)2
2C-G-3 (CH2)3 207740-19-0
2C-G-4 (CH2)4 952006-59-6
2C-G-5 (CH2)5 207740-20-3
2C-G-6 (CH2)6
2C-G-N (CH)4 207740-21-4
2C-H H H 3600-86-0
2C-I H I 69587-11-7
2C-iP H CH(CH3)2 1498978-47-4
2C-N H NO2 261789-00-8
2C-NH2 H NH2 168699-66-9
2C-PYR H Pyrrolidine
2C-PIP H Piperidine
2C-O H OCH3 15394-83-9
2C-O-4 H OCH(CH3)2 952006-65-4
2C-MOM H CH2OCH3
2C-P H CH2CH2CH3 207740-22-5
2C-Ph H C6H5
2C-Se H Se CH3 1189246-68-1
2C-T H SCH3 61638-09-3
2C-T-2 H SCH2CH3 207740-24-7
2C-T-3 H SCH2C(=CH2)CH3 648957-40-8
2C-T-4 H SCH(CH3)2 207740-25-8
2C-T-5
2C-T-6
2C-T-7 H S(CH2)2CH3 207740-26-9
2C-T-8 H SCH2CH(CH2)2 207740-27-0
2C-T-9 207740-28-1
2C-T-10
2C-T-11
2C-T-12
2C-T-13 H S(CH2)2OCH3 207740-30-5
2C-T-14
2C-T-15 H SCH(CH2)2
2C-T-16 H SCH2CH=CH2 648957-42-0
2C-T-17 H SCH(CH3)CH2CH3 207740-32-7
2C-T-18
2C-T-19 H SCH2CH2CH2CH3
2C-T-21 H S(CH2)2F 207740-33-8
2C-T-21.5 648957-46-4
2C-T-22 648957-48-6
2C-T-23
2C-T-24
2C-T-25
2C-T-27 648957-52-2
2C-T-28 648957-54-4
2C-T-30
2C-T-31
2C-T-32
2C-T-33
2C-DFM : 770  H CHF2
2C-TFM H CF3 159277-08-4
2C-TFE H CH2CF3
2C-PFE H CF2CF3
2C-PFS H SF5
2C-YN H C≡CH 752982-24-4
2C-V H CH=CH2
2C-AL H CH2CH=CH2
2C-B-FLY Br 733720-95-1
2C-B-BUTTERFLY Br 502659-24-7
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