2C-B

2C-B
Clinical data
Routes of; administration	Oral, insufflation, rectal
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class F2 (Prohibited psychotropics); CA: Schedule III; DE: Anlage I (Authorized scientific use only); UK: Class A; US: Schedule I; UN: Psychotropic Schedule II;
Pharmacokinetic data
Onset of action	20–40 min. (Oral)
Elimination half-life	2.48 ± 3.20 h
Duration of action	4–12 hours depending on route of administration
Identifiers
	IUPAC name 2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine;
CAS Number	66142-81-2;
PubChem CID	98527;
DrugBank	DB01537;
ChemSpider	88978;
UNII	V77772N32H;
KEGG	C22775;
ChEBI	CHEBI:189669;
ChEMBL	ChEMBL292821;
CompTox Dashboard (EPA)	DTXSID10216332 ;
ECHA InfoCard	100.164.088
Chemical and physical data
Formula	C10H14BrNO2
Molar mass	260.131 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1cc(CCN)c(OC)cc1Br;
	InChI InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3; Key:YMHOBZXQZVXHBM-UHFFFAOYSA-N;

2C-B (4-bromo-2,5-dimethoxyphenethylamine) is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug. The substance was first synthesized by Alexander Shulgin in 1974, and gained an initial reputation for potential psychotherapeutic use, but its use has been limited to mainly recreational use. To date, there is limited scientific information regarding the drug's pharmacokinetics and pharmacological effects in humans. The existing studies primarily classify 2C-B as a stimulant, and hallucinogen, and less commonly as an entactogen, and empathogen.

2C-B, also referred to by a number of slang names, is known to circulate in the illicit market in multiple forms. Most commonly found in a powder form, less commonly in capsules or pills. For recreational use, the substance is generally consumed orally or nasally. In Shulgin's book PiHKAL, the dosage range is listed as 12–24 mg.

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