Pralidoxime

Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with atropine and either diazepam or midazolam. It is a white solid.

Pralidoxime
Clinical data
Other names1-methylpyridine-6-carbaldehyde oxime
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • C
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 2-[(hydroxyimino)methyl]-1-methylpyridin-1-ium
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.027.080
Chemical and physical data
FormulaC7H9N2O+
Molar mass137.162 g·mol−1
3D model (JSmol)
  • ON=Cc1cccc[n+]1C
  • InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1 Y
  • Key:JBKPUQTUERUYQE-UHFFFAOYSA-O Y
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