Vitamin E deficiency
Background
- Most common causes:
- Severe malabsorption (e.g. cystic fibrosis, celiac sprue, pancreatic insufficiency)
- Abetalipoproteinemia (genetic disorder)
- Chronic cholestatic liver disease (e.g. biliary atresia)
Clinical Features
- Areflexia
- Gait disturbance
- Decreased vibration and proprioception
- Ophthalmoplegia
Differential Diagnosis
Vitamin deficiencies
- Vitamin A deficiency
- Vitamin B deficiencies
- Vitamin B1 deficiency (Thiamine)
- Vitamin B3 deficiency (Pellagra)
- Vitamin B9 deficiency (Folate)
- Vitamin B7 deficiency (Biotin)
- Vitamin B12 deficiency
- Vitamin C deficiency (Scurvy)
- Vitamin D deficiency (Rickets)
- Vitamin E deficiency
- Vitamin K deficiency
Evaluation
- Plasma Vitamin E level <0.5 mg/dL
Management
- Vitamin E repletion
See Also
References
This article is issued from Wikem. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.