I'm looking to replicate this randomisation in R studio.
Key features:
A and B are the primary comparison and must have 2 by 2 cross over design (i.e., occur togeather in each sequence)
The incomplete block design should include C D E and F - comparisons of interest are C vs D and E vs F. These comparisons need to occur the same number of times within the whole design, and one comparison must occur in each sequence
C D E F need to be balanced so that they occur the same number of times in a sequence
C D E F need to be balanced so that occurr the same number of times across periods
Any help would be greatly appreciated.
Many thanks.
The code I tried below is just for the incomplete block design C,D,E,F but I can't get it to balance across periods.
library(crossdes) out=find.BIB(4,20,3, iter=1)#each dosed 6 times achieving first order balance out isGYD(out)
I had then planned to join on the A and B rand.