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I have medical images containing speckle noises, and one of my tasks is to denoise these images. I tried 8 algorithms and inspected the denoised images visually.

I want to use PSNR to quantify the process. Based on the PSNR definition, it is calculated between noisy and clean (without any noises) images.

I there any way to quantify the denoising process performance without having clean images?

Amin
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