If we're talking about consuming the service on the SAP Business Technology platform - then yes. Check the multi-tenancy docs.
The SAP Cloud SDK is a framework for consuming services and usually not the best choice for publishing them. You can use it as a proxy or data adapter, of course, if that's what you need.
For service publishing with multi-tenancy, I'd recommend looking into the direction of the Cloud Application Programming model (CAP)
Are you building OData, OpenAPI or generic REST enabled service? The SAP Cloud SDK can help to consume your service with multi-tenancy out of the box using our OData or OpenAPI code generators and type-safe clients. You can also use the SDK for testing. Please, check the details in our docs.
I'd also recommend checking if the service you're building already exists or you can adapt some other service with help of the SDK.