from win32com.client import gencache
gencache.EnsureModule('{00020813-0000-0000-C000-000000000046}', 0, 1, 2)
The script generates early binding for the application with the clsid {00020813-0000-0000-C000-000000000046}.
In the book Python Programming on Win32 it says the third and fourth values are the major and minor respectively.
I have no idea what this means and the documentation is rather poor.