What you could do is create a class that will behave like a list but would only compute the items as needed and not actually store them:
class Powerset:
def __init__(self,base):
self.base = base
def __len__(self):
return 2**len(self.base)-2 # - 2 you're excluding empty and full sets
def __getitem__(self,index):
if isinstance(index,slice):
return [ self.__getitem__(i) for i in range(len(self))[index] ]
else:
return [ss for bit,ss in enumerate(self.base) if (1<<bit) & (index+1)]
L = [0, 3, 5, 6, 8, 9, 11, 13, 16, 18, 19, 20, 23, 25, 28, 29, 30, 32, 33, 35, 36, 38, 42, 43, 44, 45, 49, 50, 51, 53, 54, 56, 57, 62, 63, 64, 65, 66, 67, 71, 76, 78, 79, 81, 82, 84, 86, 87, 90, 92, 96, 97, 98, 100, 107]
P = Powerset(L)
print(len(P)) # 36028797018963966
print(P[:10]) # [[0], [3], [0, 3], [5], [0, 5], [3, 5], [0, 3, 5], [6], [0, 6], [3, 6]]
print(P[3:6]) # [[5], [0, 5], [3, 5]]
print(P[-3:]) # [[5, 6, 8, 9, 11, 13, 16, 18, 19, 20, 23, 25, 28, 29, 30, 32, 33, 35, 36, 38, 42, 43, 44, 45, 49, 50, 51, 53, 54, 56, 57, 62, 63, 64, 65, 66, 67, 71, 76, 78, 79, 81, 82, 84, 86, 87, 90, 92, 96, 97, 98, 100, 107], [0, 5, 6, 8, 9, 11, 13, 16, 18, 19, 20, 23, 25, 28, 29, 30, 32, 33, 35, 36, 38, 42, 43, 44, 45, 49, 50, 51, 53, 54, 56, 57, 62, 63, 64, 65, 66, 67, 71, 76, 78, 79, 81, 82, 84, 86, 87, 90, 92, 96, 97, 98, 100, 107], [3, 5, 6, 8, 9, 11, 13, 16, 18, 19, 20, 23, 25, 28, 29, 30, 32, 33, 35, 36, 38, 42, 43, 44, 45, 49, 50, 51, 53, 54, 56, 57, 62, 63, 64, 65, 66, 67, 71, 76, 78, 79, 81, 82, 84, 86, 87, 90, 92, 96, 97, 98, 100, 107]]
Obviously, if the next thing you do is a sequential search or traversal of the powerset, it will still take forever.