In addition to @mathew-taylor's suggestion, you may need to also consider the monitor, since it will need to discard partially assembled data collections.
If you have a reactive driver, this gets even trickier. It would be prudent to provide an boolean validity attribute in your transactions. Construction would set it to true (1'b1). If responses are outstanding upon reset, send all the outstanding responses after setting the validity field to false (1'b0). This will keep the sequencer from jamming. Any consumer of transaction data would then need to examine the validity. To simplify, you could build in the check via accessor functions and make all attributes local. This would also work on the monitor.