Solution 1
First try adding the PPA of the repo you need.
If you go to the repo here.
Add the PPA for the right version(my example is for version
sudo add-apt-repository ppa:c2d4u.team/c2d4u4.0+
sudo apt-get update
Then add the repo url to the source.list.
First, take a backup of your /etc/apt/source.list
sudo cp /etc/apt/source.list /etc/apt/source.bak
Replace This
https://ftp.ussg.iu.edu/CRAN/bin/linux/ubuntu xenial/ Release
With this
deb https://cloud.r-project.org/bin/linux/ubuntu xenial-cran40/
In your /etc/apt/source.list
Lastly try updating again.
sudo apt-get update
sudo apt-get upgrade
Solution 2
You might need to point apt-get to the archived repos.
I dont recognize your repo URL. From my experience If you are on a Xenial, your source list should not have bionic in it.
Have you tried these repositories?
# deb cdrom:[Ubuntu 16.04 LTS _Xenial Xerus_ - Release amd64 (20160420.1)]/ xenial main restricted
deb http://archive.ubuntu.com/ubuntu xenial main restricted universe multiverse
deb-src http://archive.ubuntu.com/ubuntu xenial main restricted universe multiverse
deb http://archive.ubuntu.com/ubuntu xenial-updates main restricted universe multiverse
deb-src http://archive.ubuntu.com/ubuntu xenial-updates main restricted universe multiverse
deb http://archive.ubuntu.com/ubuntu xenial-backports main restricted universe multiverse
deb-src http://archive.ubuntu.com/ubuntu xenial-backports main restricted universe multiverse
deb http://archive.ubuntu.com/ubuntu xenial-security main restricted universe multiverse
deb-src http://archive.ubuntu.com/ubuntu xenial-security main restricted universe multiverse
# deb http://archive.ubuntu.com/ubuntu xenial-proposed main restricted universe multiverse
deb http://archive.canonical.com/ubuntu xenial partner
deb-src http://archive.canonical.com/ubuntu xenial partner
I hope you have a full backup of this server. From my experience replacing apt list with the wrong repos could break applications and the whole OS.
Anyhow if it really is xenial repo you are after.
First, take a backup of your /etc/apt/source.list
sudo cp /etc/apt/source.list /etc/apt/source.bak
Next copy and paste the repos i provided above.
sudo nano /etc/apt/source.list
Paste the list in with the nano editor or your prefered editor.
Save the file with: ctrl+O
Close the file with: ctrl+X
Lastly try updating again.
sudo apt-get update
sudo apt-get upgrade