Apart from a couple of things (e.g. only write after erase, timings, alignment, lock/unlock) their ain't much difference between writing to RAM and writing to FLASH memory. So if you have followed the steps from the reference manual and the FLASH memory is ready (i.e. cleared and unlocked) then you can simply take an aligned memory address and write to it.
STMs very own HAL library contains a function which does all the cumbersome boilerplate for you and allows you to "just write":
HAL_StatusTypeDef HAL_FLASH_Program(uint32_t TypeProgram, uint32_t Address, uint64_t Data)
Internally this function uses a subroutine which performs the actual write and it looks like this:
static void FLASH_Program_DoubleWord(uint32_t Address, uint64_t Data)
{
/* Check the parameters */
assert_param(IS_FLASH_PROGRAM_ADDRESS(Address));
/* Set PG bit */
SET_BIT(FLASH->CR, FLASH_CR_PG);
/* Program first word */
*(__IO uint32_t*)Address = (uint32_t)Data;
/* Barrier to ensure programming is performed in 2 steps, in right order
(independently of compiler optimization behavior) */
__ISB();
/* Program second word */
*(__IO uint32_t*)(Address+4U) = (uint32_t)(Data >> 32);
}
As you can see there is no magic involved. It's just a dereferenced pointer and an assignment.