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I want to make thousands of entrez requests. I know that you are not allowed to make more than 3 requests per second unless you have an API key. The rentrez introduction says that rentrez enforces this limit.

I just want to make sure that NCBI does not block me, so the performance is not the issue here.

https://cran.r-project.org/web/packages/rentrez/vignettes/rentrez_tutorial.html

But what if I combine lapply() with entrez_search()?

authors <- c("Uhelski ML", "Manjavachi MN")
authors_pubs <- lapply(authors, function(x) entrez_search(db = "pubmed",term = paste0(x, "[AUTH]"), use_history = TRUE))

Does rentrez still enforces the request limit in this case or do I have to introduce stops into my code?

Werner Hertzog
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