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I would like an estimation of the cumulative hazard in a function that includes random (and fixed) effects. The estimation should be semi-parametric (estimation with splines, piecwise constant exponential, etc)

I tried the R package frailtypack but the additivePenal function does not work good (it does not converge with a strata term).

Does anyone have a suggestion of a R function to get estimates of the survival function (with a strata term) and random effects ?

Thanks a lot !

Flora Grappelli
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  • https://cran.r-project.org/web/views/Survival.html might be of interest? – Robert Feb 06 '19 at 10:53
  • I haven't used it for a few years, but the `coxme` package is the first hit when I search for "survival random effects in r". Same maintainer as the `survival` package, which is promising. – Gregor Thomas Feb 06 '19 at 11:08
  • @Gregor :'coxme' does not provide an estimation of the survival function... I already checked this package. Thanks ! – Flora Grappelli Feb 06 '19 at 11:28
  • @Rob: I found the `frailtyEM` package on the page Survival that might be appealing. Thanks :-) – Flora Grappelli Feb 06 '19 at 11:30

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