From the point of view of graphical data representation there is not much difference between graphics::plot
and ggplot2::autoplot
+ ggfortify
package for time-series plotting. The difference will be obvious if you will start to plot more complex plot (facetting, multiplot, grouping etc.). As for your question please see below:
graphics::plot:
data(AirPassengers)
AP <- AirPassengers
plot(AP, xlab="Date", ylab = "Passenger numbers (1000's)", main = "Air Passenger data, base")

ggplot2::autoplot:
library(ggplot2)
library(ggfortify)
data(AirPassengers)
AP <- AirPassengers
autoplot(AP) +
labs(x ="Date", y = "Passenger numbers (1000's)", title = "Air Passengers from, ggplot2")
