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I`m running the following commands to get the data from GEO

library(GEOquery)
gset <- getGEO("GSE9476", GSEMatrix =TRUE, AnnotGPL=TRUE)

But, faced the following error

https://ftp.ncbi.nlm.nih.gov/geo/series/GSE9nnn/GSE9476/matrix/ Error in function (type, msg, asError = TRUE) : error:1407742E:SSL routines:SSL23_GET_SERVER_HELLO:tlsv1 alert protocol version

SymbolixAU
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mhd
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  • This might be a bug. Try setting GSEMatrix to False as a temporary solution. – DCZ Apr 19 '18 at 10:33
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    Cannot reproduce on my machine. Related to [this issue](https://stackoverflow.com/questions/43843204/r-error-when-using-geturl-from-curl-after-site-was-changed). I'd suggest upgrading to the latest GEOquery, RCurl and OpenSSL library if you have not. – neilfws Apr 19 '18 at 10:34
  • Thank you for your reply, How can I upgrade GEOquery,RCurl,.. – mhd Apr 19 '18 at 10:43
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    @mhd try `install.packages(c("GEOquery", "RCurl"))`. – Roman Luštrik Jun 13 '18 at 10:42

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