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I'm trying to install vcftools on mac. Looking at previous posts on this issue, I made sure I've got Mac OS X developer tools (http://www.cnet.com/how-to/install-command-line-developer-tools-in-os-x/). I followed the procedure recommended in the official documantion (https://vcftools.github.io/examples.html). When I run from the command line:

./configure.ac

I get the following errors:

./configure.ac: line 4: syntax error near unexpected token [2.63]' ./configure.ac: line 4:AC_PREREQ([2.63])'

If I try:

./configure

It says:

-bash: ./configure: No such file or directory

as indeed there in no ./configure when I inspect the contents with:

ls

Can anyone point out where I am doing wrong. I've tried resources such as 'homebrew' but I didn't help.

Thanks a lot.

zx8754
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FcmC
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  • How did you download it? I pulled the latest tar file from https://github.com/vcftools/vcftools/releases, downloaded it and I see the `configure` script in there. – tk421 Mar 29 '18 at 23:30

2 Answers2

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you can download it from 

git clone https://github.com/vcftools/vcftools.git
cd vcftools

you will need to install autoconf, pkg-config, libtools, automake, and zlib.

run 

./autogen.sh

then 

./configure

follow the instructions here: https://github.com/vcftools/vcftools

YF_bio
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I was having the same issue. Basically you need to install automake. This can be done using 

brew install automake

Check this out https://www.biostars.org/p/306802/

Onkar
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  • I don't understand the downvote...this is something I tried and it works. I was facing the same problem as the OP – Onkar Sep 11 '19 at 09:00