There are a variety of good tools out there for source code and API documentation (doxygen, Headerdoc, Sphinx, to name but a few). However, none of them appear especially good at producing documentation for APIs that are provided via an RPC interface (if you have recommendations on how to synthesize RPC API documentation with these tools, by all means suggest it).
I am specifically interested in documentation tools which have at least some support for JSON and AMQP, but the question would also stand for things like Protobuf, Thrift, and XML-RPC and any tool suggestions that work with those technologies would at least give me a place to start.
I honestly have yet to see quality documentation for any RPC interface (either produced by hand or by a tool), and I'm just hoping that's because developers are lazy and not because the tools don't exist.