I am loading, doing some changes, and saving a Sales Order. I do this on approve and everything works. I do this on edit (when the status is changed to Pending Approval) and it throws the above error: "An error occurred while processing item options."
Now I have commented out the setting of 2 fields I was setting. It still throws the error.
The only thing that comes up in SuiteAnswers doesn't really make sense to this situation.