For example, I want the page to play an audio file while at the same time have some bullets slide into view at just the right moment that said bullet is talked about in the audio file. A similar effect would also be used for closed captioning. When I say reliable I mean specifically that the timing will be consistent across many common platforms (browser/OS/CPU/etc) as well as consistent in different sessions on the same platform (they hit refresh, it works again just as it did before, etc).
NOTE: It's OK if the answer is 'NO', but please include at least a little quip about why that is.