This is a very similar problem to this Win 10 Universal App with Cordova trying to load flash
This app was running fine around 3 weeks ago. It loads video from a CDN, and this seems to be related to the problem.
The error is showing 4 times and seems to stop the video from playing.
APPHOST9603: Can’t load the ActiveX plug-in that has the class ID '{D27CDB6E-AE6D-11CF-96B8-444553540000}'. Apps can't load ActiveX controls.
There is also an error when it tries to load Fonts.. so I assume it's related.
There is no ActiveX plugins or anything else being used. It's all HTML5 with WebGL. I don't think I've updated Visual Studio or changed anything.
It makes no sense as to where this has come from.