Many years later, this is how I would do this. Keeping everything in GeoPandas to minimise the possibility of footguns.
Some imports:
import pandas as pd
import geopandas as gpd
from shapely.geometry import Point
Create a dataframe (note the values must be in metres!)
df = pd.DataFrame({"X": [50e3, 900e3], "Y": [20e3, 900e3]})
Create geometries from the X/Y coordinates
df["geometry"] = df.apply(lambda row: Point(row.X, row.Y), axis=1)
Convert to a GeoDataFrame, setting the current CRS.
In this case EPSG:3857, the projection from the question.
gdf = gpd.GeoDataFrame(df, crs=3857)
Project it to the standard WGS84 CRS in degrees (EPSG:4326).
gdf = gdf.to_crs(4326)
And then (optionally), extract the X/Y coordinates in degrees back into standard columns:
gdf["X_deg"] = gdf.geometry.apply(lambda p: p.x)
gdf["Y_deg"] = gdf.geometry.apply(lambda p: p.y)