Could not load type 'Microsoft.SqlServer.Dts.Runtime.Wrapper.IDTSPackageSigning100' from assembly 'Microsoft.SqlServer.DTSRuntimeWrap, Version=10.0.0.0, Culture=neutral, PublicKeyToken=89845dcd8080cc91'
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Try unchecking the folowing setting in SQL Server Business Intelligence Studio:
Tools - Options - Business Intelligence Designers - Integration Services Designers - General - Check digital signature when loading a package
It worked for me

Daniel Dyson
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I also had the same issue. Disabling "Check digital signature when loading a package" did not work for me. After some time I realized that I had forgotten to register my assembly in the GAC. I also had to work with embedded resources for third partly libraries.

Desmond Nzuza
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