You can't force the computer to launch Audacity in itself, this is up to users preference. What you can do, is prompt a download of the file to the client, whom browser will probably propose him to open it via a list of application that handle the file extension or to download it. You can achieve that like this:
var mime = require('mime'),
fs = require('fs');
app.get('link/to/wav/on/server', function(req, res){
var file = 'filelocationOnTheServer.wav';
res.setHeader('Content-disposition', 'attachment; filename=nameYouWantToGiveit.wav');
res.setHeader('Content-type', 'audio/wav'); // This will make the browser to use the most appropriate app according to it's preference.
// res.setHeader('Content-type', 'application/octet-stream'); // This will never match to anything and will push the browser to ask the user what to do and to download it.
fs.createReadStream(file).pipe(res);
});