This is quite a broad question but yes this is possible, with using the .NET COM interop
A StackOverflow post here goes over something similar that you could use the get the details from the email received.
Code from the above post:
import win32com.client
import pythoncom
import re
class Handler_Class(object):
def OnNewMailEx(self, receivedItemsIDs):
# RecrivedItemIDs is a collection of mail IDs separated by a ",".
# You know, sometimes more than 1 mail is received at the same moment.
for ID in receivedItemsIDs.split(","):
mail = outlook.Session.GetItemFromID(ID)
subject = mail.Subject
try:
# Taking all the "BLAHBLAH" which is enclosed by two "%".
command = re.search(r"%(.*?)%", subject).group(1)
print command # Or whatever code you wish to execute.
except:
pass
outlook = win32com.client.DispatchWithEvents("Outlook.Application", Handler_Class)
#and then an infinit loop that waits from events.
pythoncom.PumpMessages()
Excel
You would then continue to use interop for excel with quite an extensive tutorial here.