I configured apache httpd to apply substitute. For my eyes it is exactly what the doc says. However it does simply nothing.
What is wrong with it?
<VirtualHost domain:443>
SSLEngine on
....
ProxyPass /cms/ http://domain2/
ProxyPassReverse /cms/ http://domain2/
Substitute "s|div|DIV|ni"
</VirtualHost>
(Apache 2.4.16 on Centos)