In Symfony2, in the extension file of a bundle, it is possible to call:
$this->addClassesToCompile([class1, ....])
This adds the given files to the cached file classes.php => this can improve performances if we put here the most used classes, because the PHP process only have to find and process 1 file insteaf many.
But with the 5.6 version of PHP, there is OPcache that can also cache files and also precompile them. So I guess that the Symfony part isn't necessary anymore?