DAMs have specific functionality tailored towards visual content. For example, DAM systems will create previews for the files stored and also, possibly, extract metadata from the file itself. In addition to that, it will also provide you options to transform and download content in various formats. Considering that all these options are part of the DAM package, I would not expect too much from them with respect to previews, metadata extraction and transformations when it comes to large binary files, such as ISO and IMG files.
You can however, use most of the DAMs to upload any file you want. It will simply take it and allow you to tag metadata against it. An example would be Elvis DAM where you can simply upload content (I would use hot folder type of uploads for large files) and tag them with metadata. You can create custom fields such as OS version, applications, etc. and store it against the ISO files. These will become searchable and it will scale to hold all of this information and allow you to quickly find your content.
There might be other simpler and less expensive solutions out there that might just simply keep a file and assign metadata to it.