I ran into this issue recently - when I try to replace the Wix Product version number using NANT XMLPOKE task, it returns the following error message "No matching nodes found".
<xmlpoke file="..\Setup\abc.wxs" xpath="//Wix/Product[@Version]" value="${version.label}" >
Initially I thought that this was an issue with XPATH statement that I wrote. So I kept trying with different XPATH (like \Wix) and I kept getting the same message back.
Understood from a blog that this is happening due to the namespace definition with the WiX element. Please find below the solution, in case someone doesn't find the blog.