If you really need that compression, you could use the fact that a pptx is just a fancy zip file:
Unzip the pptx, then compress it with 7zip. To recover an equivalent (but not identical) pptx decompress with 7zip and recompress with zip.
There are probably some complications, for example with epub there is a certain file that must be stored uncompressed as first file in the archive at a certain offset from the start. I'm not familiar with pptx, but it might have similar requirements.
I think it's unlikely that the small reduction in file size is worth the trouble, but it's the only approach I can think of.
Depending on what's responsible for the size of the pptx you could also try to compress the contained files. For example by recompressing png files with a better compressor, stripping unnecessary data (e.g. meta-data or change histories) or applying lossy compression with lower quality settings for jpeg files.