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I am using GA to minimize the objective function which has 24 design variables. All the variables have only upper and lower bounds but last 4 variables have x and y axis constraint. How to do this in MatLab Since the bound constraint can only be feed to GA as a vectors. Please help.

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if your variables are dependent on x and y then you can try to find the min and max value of variable for given range of values of x and y and then use those values to define upper and lower bound